Case Control Study
Copyright ©The Author(s) 2022.
World J Clin Cases. Jun 16, 2022; 10(17): 5551-5565
Published online Jun 16, 2022. doi: 10.12998/wjcc.v10.i17.5551
Table 4 Effects of biliary drainage
During biliary obstruction (n = 55)
48 h after drainage (n = 55)
28 d after drainage (n = 55)
P value1
Bilirubin (mmol/L)145 (63.9-230.7)88.5 (38.75-190.5)25 (18.85-38.7)< 0.001
ALT (U/L)133 (78-194)91.5 (63.75-144.25)30 (23-46.5)< 0.001
GGT (U/L)278 (103-421)194 (103.25-267.25)36 (28-64)< 0.001
ALP (U/L)448 (288.5-612.5)382.5 (184-606.5)85 (61-111)< 0.001
AST (U/L)284 (260.5-382)281.5 (231.75-429.25)123 (103.5-166)< 0.001
CRP (mg/L)10.0 (5.8-14.1)17.9 (5.9-26.8)8.3 (2.5-17.3)0.009
IL-6 (pg/mL)9 (6-13)11 (7-22)9 (5-21.5)0.332
TNF-α (pg/mL)11 (8.5-13)10 (9-12)10 (8-12.5)0.088
Ghrelin (pg/mL)1549 (1079.5-2400.5)1648.5 (1137.25-2767)1612 (891.5-2962)0.552
Cholecystokinin (pg/mL)213.0 (161.0-380.7)266.0 (203.0-400.5)235.0 (158.0-433.0)0.03
Albumin (g/L)37.1 (33.0-40.8)35.0 (32.4 -38.0)38.0 (35.0-42.0)< 0.001
Appetite (VAS)4 (2-6)6 (4-8)7 (6-9)< 0.001
BMI (kg/m2)24.5 (21.3-28.2)24.4 (20.6-27.9)24.9 (21.2-26.8)< 0.001
Body fat (%)23 (17-25)23 (17-24)23 (19-25)0.002
NRS 20023.0 (2.0-4.0)3.5 (2.0-4.0)0.0 (0.0-4.0)< 0.001
1Friedman test across three observations.
Values are presented as median (Q1-Q3); ALT: Alanine aminotransferase; GGT: Gamma-glutamyl transferase; ALP: Alkaline phosphatase; AST: Aspartate aminotransferase; CRP: C-reactive protein; IL-6: Interleukin 6; TNF-α: Tumor necrosis factor α; VAS: Visual analog scale; BMI: Body mass index; NRS: Nutritional risk screening.