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Copyright ©The Author(s) 2022.
World J Clin Cases. Jun 6, 2022; 10(16): 5146-5155
Published online Jun 6, 2022. doi: 10.12998/wjcc.v10.i16.5146
Table 2 Examples of nanodevices currently under investigation for gastrointestinal cancer
NP type
GI cancer
Application
Ref.
SPIONColorectal; liver; gastricLymph node staging, detection of small metastatic lymph nodes.; magnetic NP-based biosensors for detection of biomarkers; companion diagnostics, evaluate accumulation and predict treatment efficacy of nanomedical cancer therapy[35,64,71]
QDsColorectal; liver; gastricCancer targeting and imaging; NIR-QD for simultaneous visualization of SLNs; multicolor QD probes for diagnosis of malignant tumors[41,72-74]
Carbon nanotubesColorectal; liverDetection of lymph nodes and node metastasis; tumor localization[49,52]
Gold NPsColorectal; liver; gastric; pancreatic; esophagealPhotothermal effect; hyperthermia and cellular destruction; X-ray and CT contrast agents; targeted drug delivery[75-80]
DendrimersPancreatic; colorectalDual targeting imaging; targeted drugs delivery and gene therapy; boron neutron capture therapy.[60,81,82]
NanoshellGastricContrast agents; targeted drugs delivery and gene therapy[42,77]
PolymersColorectal; gastric; pancreatic; esophagealControlled drug delivery systems[83-85]