Familial gastrointestinal stromal tumors with KIT germline mutation in a Chinese family: A case report

Figure 2 Clinical features of pigmented lesions of patient 1 (III: 1). A: Hyperpigmentation with well-defined margin was observed on the face; B: Around the mouth and on back of the lower limbs; C: Before initiation of imatinib therapy there was apparent pigmentation on the hand; D and E: After 7 mo of imatinib therapy, the pigmentations diminished, and the skin tone became lighter.