Reduced serum high-density lipoprotein cholesterol levels and aberrantly expressed cholesterol metabolism genes in colorectal cancer

Figure 3 Correlation of differentially expressed gene expression and disease-free survival in patients with colorectal cancer. The survival curves comparing the patients with high (red) and low (blue) expression were plotted from the PrognoScan database. A-C: High mRNA expression of low-density lipoprotein receptor, ABCA1 and OSBPL1A was an unfavorable prognostic factor for disease-free survival (DFS) in colorectal cancer (CRC) patients; D: High mRNA expression of FDXR was a favorable prognostic factor for DFS in CRC patients; E-G: Lipoprotein receptor-related protein 8, PCSK9 and MBTPS2 expression could not be used to predict DFS outcome according to the results of this analysis.