Mixed porokeratosis with a novel mevalonate kinase gene mutation: A case report

Table 1 Clinical features of patients with coexisting disseminated superficial actinic porokeratosis and porokeratosis ptychotropica

Ref.	Gender	Age	Ethnicity	Nationality	Clinical variants	Genetics	Risk factors	Treatment
Thomas et al[21]	Female	78 yr	NA	United Kingdom	DSAP, Ppt	NA	None	NA
McGuigan et al[7]	Male	84 yr	NA	United States	DSAP, Ppt	NA	Sun exposure, non-melanoma skin cancer	0.025% tretinoin cream, 0.05% tazarotene cream.
Murase et al[22]	Female	73 yr	Korean	Korea	DSAP, Ppt linear porokeratosis	NA	Family history	NA
Peng et al[23]	Male	70 yr	Chinese	China	DSAP, Ppt	MVK missense mutation (c.1039G>C, p.Gl- y347Arg)	Family history	Oral acitretin (20 mg daily)
Our patient	Male	45 yr	Chinese	China	DSAP, Ppt	MVK missense mutation (c.155G>A, p.Ser52Asn)	Family history	Microwave knife

DSAP: Disseminated superficial actinic porokeratosis; Ppt: Porokeratosis ptychotropica; MVK: mevalonate kinase; NA: Not available.