Cutaneous mucosa-associated lymphoid tissue lymphoma complicating Sjögren's syndrome: A case report and review of literature

Table 1 Clinical characteristics of the 142 Sjögren's syndrome patients with mucosa-associated lymphoid tissue lymphoma reported in the literature

Patients characteristics	SS with MALT lymphoma (n = 142)
Age of SS diagnosis, mean year	45
Age of lymphoma onset, mean year	54
Female, n (%)	133/142 (93.7)
Dry eye, n (%)	45/108 (41.7)
Dry mouth, n (%)	45/108 (41.7)
Parotid gland swelling, n (%)	51/102 (50.0)
Fatigue, decreased appetite, or weight loss, n (%)	26/96 (27.1)
Cryoglobulinemia or cryoglobulinemic vasculitis, n (%)	10/77 (13.0)
ANA positive, n (%)	104/113 (92.0)
Anti-Ro/SSA positive, n (%)	100/113 (88.5)
Anti-La/SSB positive, n (%)	41/107 (38.3)
Monoclonal gammopathy, n (%)	37/82 (45.1)
RF positive, n (%)	87/102 (85.3)
Low C4, n (%)	31/77 (40.3)
Positive SG biopsy, FS ≥ 1, n (%)	36/41 (87.8)
Lymphoma location Parotid gland, n (%)	110 (77.5)
Lung, n (%)	21 (14.8)
Thymus, n (%)	8 (5.6)
Lymph nodes, n (%)	6 (4.2)
Bone marrow, n (%)	5 (3.5)
Submandibular glands, n (%)	3 (2.1)
Lacrimal gland, n (%)	2 (1.4)
Other sites, n (%) (stomach, breast, tongue, spleen, liver, kidney, mouth, lip)	9 (6.3)

SS: Sjögren's syndrome; MALT: Mucosa-associated lymphoid tissue; RF: Rheumatoid factor; SG: Salivary gland.