Reduced serum high-density lipoprotein cholesterol levels and aberrantly expressed cholesterol metabolism genes in colorectal cancer

Table 3 Relationship between colorectal tumor staging and serum cholesterol levels

Project (stage)	I (n = 151)	II (n = 296)	III (n = 340)	IV (n = 56)	P value
TC	4.61 ± 0.86	4.55 ± 0.88	4.65 ± 1.01	4.30 ± 0.94	0.395
TG	1.44 ± 0.95	1.31 ± 0.79	1.4 ± 0.87	1.09 ± 0.85	0.228
HDL-C	1.3 ± 0.35	1.22 ± 0.38	1.2 ± 0.37	1.24 ± 0.37	0.045
LDL-C	3.01 ± 0.78	3.04 ± 0.8	3.11 ± 0.91	2.81 ± 0.85	0.427
TC/LDL-C	1.57 ± 0.18	1.54 ± 0.22	1.55 ± 0.3	1.58 ± 0.25	0.689
TC/HDL-C	3.78 ± 1.17	3.96 ± 1.15	4.19 ± 1.44	3.65 ± 1.29	0.006
LDL-C/HDL-C	2.5 ± 0.95	2.66 ± 0.97	2.8 ± 1.06	2.4 ± 1.01	0.014

TC: Total cholesterol; TG: Triglyceride; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol.