Hematopoiesis reconstitution and anti-tumor effectiveness of Pai-Neng-Da capsule in acute leukemia patients with haploidentical hematopoietic stem cell transplantation

Table 1 Characteristics of the participants

Characteristics	Non-PND group (n = 31)	PND group (n = 29)	P value
Age (yr)			0.441
Median	33	37
Range	3–63	2–62
Males, n (%)	17 (54.8)	18 (62.1)	0.609
Diagnosis, n (%)			0.793
Acute myeloid leukemia	19 (61.3)	19 (65.5)
Acute lymphocytic leukemia	12 (38.7)	10 (34.5)
High cytogenetic risk, n (%)	11 (35.5)	12 (41.4)	0.791
Courses of chemotherapy before transplantation			0.819
Median	3	3
Range	2–7	2–8
Disease status at transplantation, n (%)			0.758
First complete remission	25 (80.6)	22 (75.9)
Second complete remission	6 (19.4)	7 (24.1)
Peripheral blood cell counts (pre-transplantation)
Neutrophil count (109/L)			0.824
Median	1.5	1.25
Range	0.45-6.21	0.42-6.77
Hemoglobin concentration (g/L)			0.773
Median	92	86
Range	68-130	72-142
Platelet count (109/L)			0.636
Median	87	83
Range	34-310	45-275
Donor’s age (yr)			0.668
Median	34	39
Range	9–62	10–63
Female donor–male recipient pairs, n (%)	7 (22.6)	8 (27.5)	0.769
Cytomegalovirus IgG-positive recipients, n (%)	16 (51.6)	13 (44.8)	0.617
Infused mononuclear cells (× 108/kg)			0.270
Median	12.42	14.67
Range	8.39–44.41	7.93–39.44
Infused CD34 + cells (× 106/kg)			0.243
Median	4.32	3.72
Range	1.20–7.47	1.03–10.80

PND: Pai-Neng-Da.