High plasma CD40 ligand level is associated with more advanced stages and worse prognosis in colorectal cancer

Table 2 Clinico-histopathological features of colorectal cancer patients

Parameter	Number of observations
AJCC staging[16], n (%)
Stage I	27 (25.5)
Stage II	26 (24.5)
Stage III	24 (22.6)
Stage IV	29 (27.4)
Regional lymph node metastasis, n (%)
N0	57 (53.8)
N1+	49 (46.2)
Development of distant metastasis after the tumor removal surgery, n (%)	14 (13.2)
Side of CRC, n (%)
Left-sided	75 (70.8)
Right-sided	31 (29.2)
Chemotherapy, n (%)
None	51 (48.1)
Adjuvant	21 (19.8)
First-line	11 (10.4)
Second-line	13 (12.3)
Third or later-line	10 (9.4)
Usage of biological therapy, n (%)	22 (20.8)

AJCC: American Joint Committee on Cancer; CRC: Colorectal cancer.