Three-dimensional echocardiographic assessment of left ventricular volume in different heart diseases using a fully automated quantification software

Table 3 Comparison of left ventricular volume and left ventricular ejection fraction measured by M-mode echocardiography, Biplane Simpson, and HeartModel methods against advanced cardiac three-dimensional quantification

Parameter	rs	Bias ± LOA	Relative bias (%)	Percentage error (%)
Teichholz (n = 150)
LVEDV (mL)	0.82	37.3 ± 82.7	35.1	66.1
LVESV (mL)	0.91	20.0 ± 56.2	35.8	85.2
LVEF (%)	0.89	1.5 ± 12.3	3.0	23.5
Biplane Simpson (n = 150)
LVEDV (mL)	0.87	4.6 ± 46.8	4.3	43.0
LVESV (mL)	0.94	1.9 ± 26.9	3.4	47.2
LVEF (%)	0.91	1.4 ± 11.8	2.7	22.6
LAESV (mL)	0.93	0.7 ± 23.7	1.2	39.6
3DQ (n = 150)
LVEDV (mL)	0.96	2.4 ± 21.3	2.3	19.8
LVESV (mL)	0.98	1.3 ± 11.2	2.3	19.8
LVEF (%)	0.98	0.1 ± 5.2	0.2	10.1
HM-NE (n = 150)
LVEDV (mL)	0.85	33.4 ± 56.4	31.4	45.8
LVESV (mL)	0.90	15.7 ± 33.0	28.0	51.6
LVEF (%)	0.85	-0.2 ± 16.8	-0.4	-32.5
LAESV (mL)	0.93	10.2 ± 30.3	17.2	47.0
HM-RE (n = 150)
LVEDV (mL)	0.91	28.1 ± 47.6	26.4	39.5
LVESV (mL)	0.93	14.92 ± 30.9	26.6	48.7
LVEF (%)	0.95	-0.0 ± 9.8	-0.0	-19.0
LAESV (mL)	0.95	8.1 ± 23.7	13.7	37.4

Relative bias = (parametermethod-parameter 3DQA)/parametermethod; Percentage error = LOA/mean value of parameter measured by studied method and 3DQA. LOA: Limits of agreement; 3DQA: Advanced cardiac three-dimensional quantification; 3DQ: Cardiac three-dimensional quantification; HM-NE: HeartModel without regional endocardial border editing; HM-RE: HeartModel with regional endocardial border editing; LVEDV: Left ventricular end-diastolic volume; LVESV: Left ventricular end-systolic volume; LVEF: Left ventricular ejection fraction; LAESV: Left atrial end-systolic volume; DCM: Dilated cardiomyopathy; SWMA: Segmental wall motion abnormality; HCM: Hypertrophic cardiomyopathy.