Anorectal dysfunction in patients with mid-low rectal cancer after surgery: A pilot study with three-dimensional high-resolution manometry

Table 3 Comparison of anorectal functions detected by three-dimensional high-resolution anorectal manometry before and after surgery

Parameter	Total (n = 24)		Surgery only group (n = 6)		Neoadjuvant group (n = 18)
	Before surgery	After surgery	Before surgery	After surgery	Before surgery	After surgery
Length of high pressure zone of anal sphincter (cm)	3.6 ± 0.7	2.8 ± 1.2a	3.6 ± 0.5	3.6 ± 1.1	3.6 ± 0.7	2.6 ± 1.2a
Mean resting pressure of the anus (mmHg)	107.6 ± 32.3	67.6 ± 28.1a	102.9 ± 38.9	75.2 ± 37.2a	109.2 ± 30.9	65.1 ± 25.2a
Maximal squeeze pressure (mmHg)	259 ± 80.0	207.8 ± 63.3a	274.9 ± 109.6	249.8 ± 89.7	253.7 ± 70.8	193.8 ± 47.2a
First perception of rectal filling volume (mL)	35.6 ± 19.7	39.2 ± 25.8 (n = 12)	20.0 ± 14.1	25.0 ± 7.1 (n = 2)	43.0 ± 27.5	42.0 ± 27.4 (n = 10)
Urgency to defecate volume (mL)	60.0 ± 24.3	51.4 ± 31.9 (n = 7)	35.0 ± 21.2	35.0 ± 7.1 (n = 2)	66.0 ± 18.2	58.0 ± 36.3 (n = 5)
Maximal tolerable volume (mL)	112.1 ± 42.1	71.4 ± 21.2 (n = 7)	123.3 ± 64.3	60.0 ± 26.5 (n = 3)	110.0 ± 11.6	80.0 ± 14.1 (n = 4)

^aP < 0.05.

Data are expressed as the mean ± SD. A paired t-test was used to compare the data before vs after surgery. The numbers of patients who acquired the first perception of rectal filling volume, urgency to defecate volume, and maximal tolerable volume after surgery are listed in brackets, and those data were not compared for the difference between before and after surgery.