Anorectal dysfunction in patients with mid-low rectal cancer after surgery: A pilot study with three-dimensional high-resolution manometry

Table 2 Low anterior resection syndrome score in patients with mid-low rectal cancer at 3 and 6 mo after surgery

Item (scale point)	3 mo after surgery, n (%)	6 mo after surgery, n (%)	P value
Frequency of uncontrolled intestinal flatus			0.005
No, never (0)	4 (16.7)	10 (41.7)
Yes, less than once per wk (4)	1 (4.2)	8 (33.3)
Yes, at least once per wk (7)	19 (79.2)	6 (25.0)
Frequency of uncontrolled intestinal fluid			0.003
No, never (0)	5 (20.8)	13 (54.2)
Yes, less than once per wk (3)	8 (33.3)	8 (33.3)
Yes, at least once per wk (3)	11 (45.8)	3 (12.5)
Bowel frequency			0.037
> 7 times/d (4)	7 (29.2)	2 (8.3)
4-7 times/d (2)	16 (66.7)	18 (75.0)
1-3 times/d (0)	1 (4.2)	4 (16.7)
Less than once per day (5)	0 (0)	0 (0)
Clustering			0.500
No, never (0)	1 (4.2)	3 (12.5)
Yes, less than once per wk (9)	0 (0)	0 (0)
Yes, at least once per wk (11)	23 (95.8)	21 (87.5)
Urgency			0.040
No, never (0)	2 (8.3)	3 (12.5)
Yes, less than once per wk (11)	1 (4.2)	8 (33.3)
Yes, at least once per wk (16)	21 (87.5)	13 (54.2)
LARS score1	39 (1.5)	31 (7.5)	< 0.001
No LARS (0-20)	3 (12.5)	4 (16.7)
Minor LARS (21-29)	1 (4.2)	6 (25.0)
Major LARS (30-42)	20 (83.3)	14 (58.3)

¹LARS score is expressed as the median (interquartile range) and a Wilcoxon signed-ranks test was used to identify a significant difference between 3 mo and 6 mo after surgery.

LARS: Low anterior resection syndrome.