Del(5q) and inv(3) in myelodysplastic syndrome: A rare case report

Figure 1 Bone marrow aspiration biopsy, karyotype and fluorescence in situ hybridization assay at first diagnosis. A: Representative image of May Grunwald-Giemsa staining of bone marrow specimen. It is showed that more than 5% blast cell and more than 10% abnormal megakaryocytes, including unicellular megakaryocytes (panel A red arrow) and lymphatic-like small megakaryocytes (yellow arrow). B: EGR(5q31) gene was detected by fluorescence in situ hybridization. Each signal mode was detected as follows :2G1R 50%,2G2R 50%. EGR(5q31) probe was labeled with red fluorescence, D5S23 and D5S721(5p15.2) probe was labeled with green fluorescence. C: G-band bone marrow karyotype. Arrows indicate the del(5)(q13q31).