HER2 changes to positive after neoadjuvant chemotherapy in breast cancer: A case report and literature review

Figure 2 Ultrasound result after neoadjuvant chemotherapy and histopathological and fluorescence in situ hybridization findings of the resected tumor. A: Ultrasound demonstrating the tumor measuring 0.8 cm × 0.7 cm after neoadjuvant chemotherapy (arrow); B: Histopathological finding showing the tumor cells tubular arrangement and the development of invasion (H&E staining, × 50) (arrow); C: Positive control of fluorescence in situ hybridization (FISH); D: Negative control of FISH; E: FISH result of the surgically resected tumor.