Distribution of transient receptor potential vanilloid-1 channels in gastrointestinal tract of patients with morbid obesity

Table 3 Distribution and comparison of transient receptor potential vanilloid-1 in duodenal cells in the morbidly obese and control groups, n (%)

Duodenal			Obese	Control	All cases	P value
Goblet	No staining		30 (65.2)	15 (75)	45 (68.1)
	Distribution	Limited	12 (26.0)	2 (10)	14 (21.2)
		Widespread	4 (8.6)	3 (15)	7 (10.6)
	Intensity	Poor	16 (3.7)	5 (25)	21 (31.8)
		Strong	0 (0)	0 (0)	0 (0%)
	IRS (± SEM)		1.14 ± 0.25b	0.8 ± 0.34a	1.03 ± 0.2b	0.40
Absorptive	No staining		24 (52.1)	9 (45)	33 (50)
	Distribution	Limited	11 (23.9)	8 (40)	19 (28.7)
		Widespread	11 (23.9)	3 (15)	24 (36.3)
	Intensity	Poor	19 (41.3)	6 (30)	25 (37.8)
		Strong	3 (6.5)	5 (25)	8 (12.1)
	IRS (± SEM)		2.14 ± 0.41b	2.25 ± 0.56a,c	2.17 ± 0.33b,d	0.90
Mucous	No staining		31 (67.3)	15 (75)	46 (69.6)
	Distribution	Limited	12 (26.0)	3 (15)	15 (22.7)
		Widespread	3 (6.5)	2 (10)	5 (7.5)
	Intensity	Poor	9 (19.5)	5 (25)	14 (21.2)
		Strong	6 (13.0)	0 (0)	6 (9.0)
	IRS (± SEM)		1.55 ± 0.41	0.85 ± 0.39c	1.33 ± 0.31d	0.41

^aP < 0.05 vs Goblet-Absorptive cell.

^bP < 0.01 vs Goblet-Absorptive cell.

^cP < 0.05 vs Mucous-Absorptive cell.

^dP < 0.01 vs Mucous-Absorptive cell.

IRS: Immunoreactivity score.