Distribution of transient receptor potential vanilloid-1 channels in gastrointestinal tract of patients with morbid obesity

Table 1 Distribution and comparison of transient receptor potential vanilloid-1 in fundus cells in the morbidly obese and control groups, n (%)

Fundus			Obese	Control	All cases	P value
Parietal	No staining		6 (13.0)	7 (35)	13 (19.6)
	Distribution	Limited	8 (17.3)	3 (15)	11 (16.6)
		Widespread	32 (69.5)	10 (50)	42 (63.6)
	Intensity	Poor	33 (71.7)	11 (55)	44 (66.6)
		Strong	7 (15.2)	2 (10)	9 (13.6)
	IRS ± SE		5.42 ± 0.49a,c	4.84 ± 0.93a,c	5.25 ± 0.44a,c	0.60
Chief	No staining		15 (32.6)	11 (55)	26 (39.3)
	Distribution	Limited	9 (19.5)	6 (30)	15 (22.7)
		Widespread	22 (47.8)	5 (25)	27 (40.9)
	Intensity	Poor	30 (65.2)	11 (55)	41 (62.1)
		Strong	1 (2.1)	0 (0)	1 (1.5)
	IRS ± SE		2.78 ± 0.40a,e	1.74 ± 0.50a	2.47 ± 0.32a,e	0.13
Foveolar	No staining		42 (91.3)	16 (80)	58 (87.8)
	Distribution	Limited	1 (2.1)	0 (0)	1 (1.5)
		Widespread	3 (6.5)	4 (20)	7 (10.6)
	Intensity	Poor	4 (8.6)	4 (20)	8 (12.1)
		Strong	0 (0)	0 (0)	0 (0)
	IRS ± SEM		0.33 ± 0.16c,e	0.84 ± 0.38c	0.48 ± 0.16c,e	0.16

^aP < 0.01 vs Parietal-Chief cell.

^cP < 0.01 vs Parietal-Foveolar cell.

^eP < 0.01 vs Chief-Foveolar cell.

IRS: Immunoreactivity score.