Increased levels of lactate dehydrogenase and hypertension are associated with severe illness of COVID-19

Table 2 Laboratory test results of the patients (n = 140)

	Mild illness (n = 114)	Severe illness (n = 26)	P value
Leukocyte count (× 109/L)	5.01 ± 1.85	4.67 ± 1.84	0.398
Neutrophil count (× 109/L)	3.15 ± 1.41	3.55 ± 1.88	0.308
Lymphocyte count (× 109/L)	1.4 ± 0.59	0.74 ± 0.31	< 0.001
Hemoglobin (g/L)	136.13 ± 14.43	130.73 ± 15.18	0.09
Platelet count (× 109/L)	201.48 ± 72.45	164.35 ± 62.69	0.017
Alanine aminotransferase (U/L)	29.26 ± 29.67	35.69 ± 25.43	0.309
Aspartate transaminase (U/L)	27.97 ± 17.45	41.54 ± 26.22	0.017
Total serum protein (g/L)	70.27 ± 5.08	65.38 ± 5.19	< 0.001
Albumin (g/L)	45.71 ± 33.39	37.42 ± 3.55	0.209
Prealbumin (g/L)	198.66 ± 50.55	123.13 ± 47.11	< 0.001
Blood urea nitrogen (mmol/L)	3.71 ± 5.96	5.96 ± 10.91	0.303
Blood creatinine (μmol/L)	172.63 ± 34.15	159.24 ± 433.95	0.319
Blood uric acid (μmol/L)	241.84 ± 89.51	194.92 ± 96.27	0.019
Creatine kinase (U/L)	103.54 ± 180.73	211.49 ± 379.39	0.168
Lactate dehydrogenase (U/L)	202.94 ± 63.87	299.35 ± 68.82	< 0.001
C-reactive protein (mg/L)	14.61 ± 19.35	52.48 ± 29.63	< 0.001
Erythrocyte sedimentation rate (mm/h)	23.68 ± 14.36	33.25 ± 15.00	0.003
Arterial partial pressure of oxygen (kPa)	13.23 ± 4.00	11.06 ± 2.91	0.01
Oxygenation index (mmHg)	460.80 ± 138.71	324.62 ± 61.52	< 0.001