Tissue plasminogen activator via cross-collateralization for tandem internal carotid and middle cerebral artery occlusion

Figure 1 Pre and post intervention cerebral angiography. A: Left carotid occlusion from likely dissection; B: Cross filling of the left internal carotid artery distribution via right internal carotid artery injection. The left middle cerebral artery (MCA) distribution does not completely opacify due to thrombus; C: Microcatheter crossing into the left MCA via the anterior communicating artery. Intra-arteria tissue plasminogen activator was delivered; D: Magnetic resonance angiography performed 10 h later confirms patency of the left MCA branches correlating with the patient’s resolution of clinical symptoms.