Concurrent hepatocellular carcinoma metastasis to stomach, colon, and brain: A case report

Figure 1 Abdominal computed tomography. The computed tomography shows a lesion thickening the lateral wall of the stomach and another lesion partially obstructing the ascending colon (orange circle).

Figure 2 Magnetic resonance imaging of the brain. The magnetic resonance imaging shows a 3.8 mm enhanced brain metastasis with peritumoral edema in the left frontal lobe.

Figure 3 Endoscopic and colonoscopic views of the tumors. A: Endoscopic view of a bleeding, ulcerofungating mass in the stomach; B: Colonoscopic view of an ulcerofungating mass partially obstructing the ascending colon.

Figure 4 Immunohistochemical results. A: Liver; B: Stomach; C: Colon; D: Brain. CD44 expression in metastatic lesions is strongly positive compared to the primary tumor.

Figure 5 Immunohistochemical results. A: Liver; B: Stomach; C: Colon; D: Brain. E-cadherin expression of primary tumor is strongly positive compared to metastatic lesions.