Penile metastasis from rectal carcinoma: A case report

Figure 1 Imaging and macroscopic examination of the secondary penile tumour. A: Ultrasonography showed a hyper-echoic mass on the root of the left penis; B: Abdominal contrast-enhanced computed tomography indicated a nodular mass measuring 1.5 cm with mild enhancement; C: A rigid nodule with distinct margins found in the left penis during the operation; D: The resected specimen measured 1.5 cm in diameter.

Figure 2 Histopathological analysis and immunohistochemical examination of the resected specimen. A: Haematoxylin and eosin staining (×200). Immunohistochemical staining for (B) CK20 (×200), (C) CDX2 (×200), and (D) prostate-specific antigen (×200).

Figure 3 General distribution of patients with penile metastasis from rectal carcinoma. A: Distribution of patient age. The median age was approximately 60 years; B: The time to penile metastasis occurrence ranged from 4 to 312 mo, with a median time of 24 mo; C: Distribution of the size of secondary penile tumours; D: Distribution of the overall survival time after the diagnosis.

Figure 4 Risk factors for penile metastasis from rectal carcinoma. A: Poorly differentiated rectal carcinoma (P = 0.011); B: Rectal carcinoma with lymph node metastasis (P = 0.009); C: Time to the occurrence of penile metastasis < 6 mo (P = 0.009); D: Diameter of secondary penile tumour > 1 cm (P = 0.036); E: Treatment abandonment (P = 0.007).