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Copyright ©The Author(s) 2015.
World J Methodol. Jun 26, 2015; 5(2): 101-107
Published online Jun 26, 2015. doi: 10.5662/wjm.v5.i2.101
Table 1 Regimens for Helicobacter pylori treatment
Standard triple therapy (7-14 d)PPI - standard dose, bid Clarithromycin - 500 mg, bid Amoxicillin - 1 g, bid
Bismuth quadruple Therapy (10-14 d)PPI - standard dose, bid Bismuth - standard dose, qid Tetracycline - 500 mg, qid Metronidazole - 500 mg, tid
Sequential therapy (5-d dual therapy followed by a 5-d triple therapy)Dual therapy; PPI - standard dose, bid Amoxicillin - 1 g, bid Triple therapy; PPI - standard dose, bid Clarithromycin - 500 mg, bid Metronidazole - 500 mg, bid
Concomitant therapy (7-10 d)PPI - standard dose, bid Clarithromycin - 500 mg, bid Amoxicillin - 1 g, bid Metronidazole - 500 mg, bid
Hybrid therapy (7-d dual therapy followed by a 7-d quadruple therapy)Dual therapy; PPI - standard dose, bid
Amoxicillin - 1 g, bid
Triple therapy; PPI - standard dose, bid
Amoxicillin - 1 g, bid
Clarithromycin - 500 mg, bid
Metronidazole - 500 mg, bid
Levofloxacin-based triple therapy (10-d)PPI - standard dose, bid
Levofloxacin - 500 mg, qd
Amoxicillin - 1 g, bid
Rifabutin-based triple therapy (7-14 d)PPI - standard dose, bid
Amoxicillin - 1 g, bid
Rifabutin - 150 mg, qd
Culture-guided therapy (10-d)PPI - standard dose, bid
Bismuth - standard dose, qid
Two antibiotics selected by antimicrobial sensitivity tests
PPI: Proton pump inhibitor; bid: Twice daily; qd: Once daily; qid: Four times daily; tid: Three times daily.