Choosing inclusion criteria that minimize the time and cost of clinical trials

Figure 3 A sample receiver operating characteristic curve for a hypothetical screening test. In this example type 1 patients had screening scores, x, with a mean of 5.5 and a standard deviation of 1; type 2 patients had screening scores, x, with a mean of 4 and a standard deviation of 1. As the cutoff value xc is swept from 1.0 toward zero, a family of true positive and false positive fractions is created to generate the receiver operating characteristic (ROC) curve.