New prospects in the diagnosis and treatment of immune-mediated inner ear disease

Table 2 Diagnostic profile for autoimmune inner ear disease

Major criteria

Bilateral hearing loss

Systemic autoimmune disease

ANA > 1:80

Decrease of native T cells (CD4CD45RA)

Hearing recovery rate > 80%

Minor criteria

Unilateral hearing loss

Young or middle aged

Woman

Hearing recovery rate < 80%

Hearing recovery rate (after immunosuppressive therapy) is obtained: (initial hearing levels - final hearing levels)/initial hearing level – opposite ear hearing levels) × 100 (%). An autoimmune inner ear disease is suspected when three major criteria or two major and two minor criteria are met.