Choosing inclusion criteria that minimize the time and cost of clinical trials

Table 2 Raw data from a reconstructed study of cancer treatment

Class	Old	Male	Smoke	Receptor	Exp	Exp	Control	Control	x	x%
					NR count	R count	NR count	R count
1	1	1	1	1	0	0	0	0	-0.072	47
2	1	1	1	0	5	1	4	2	-0.619	0
3	1	1	0	1	0	0	0	0	0.211	71
4	1	1	0	0	6	1	4	2	-0.336	24
5	1	0	1	1	0	0	1	0	0.113	63
6	1	0	1	0	9	1	6	3	-0.434	16
7	1	0	0	1	1	3	2	2	0.396	87
8	1	0	0	0	9	1	7	3	-0.151	40
9	0	1	1	1	0	0	0	0	0.078	60
10	0	1	1	0	4	0	3	1	-0.468	13
11	0	1	0	1	0	1	1	0	0.362	84
12	0	1	0	0	4	0	3	2	-0.185	37
13	0	0	1	1	0	0	0	0	0.263	76
14	0	0	1	0	6	1	5	2	-0.283	29
15	0	0	0	1	3	6	4	4	0.547	100
16	0	0	0	0	4	1	5	3	0	53
pNR	0.588	0.373	0.471	0.078
pR	0.438	0.188	0.188	0.625
Coef- ficients	a1	a2	a3	a4
	-0.151	-0.185	-0.283	0.547