An overview of translational (radio)pharmaceutical research related to certain oncological and non-oncological applications

Figure 6 Post-mortem analysis of infarcts and viable heart tissues from rabbits with acute reperfused myocardial infarction having intravenously received iodine-123 labeled hypericin/hypericin dissolved in a 0. 07 mol/L solution of the liver-produced surfactant sodium cholate. A: A typical autoradiogram of 50-μm-thick sections reveals higher tracer uptake in infarction than in viable myocardium. The color code bar indicates the coding scheme for the radioactivity; B: Microscopic images of 50-μm-thick sections confirm the selective affinity of the highly fluorescent iodine-123-labeled-hypericin/hypericin for acute myocardial infarction in contrast to the low fluorescent signal found in viable myocardium; C: The H and E-stained section corroborates the location of the viable myocardium tissue and the presence of myocardial necrosis characterized by scattered hemorrhage.