An overview of translational (radio)pharmaceutical research related to certain oncological and non-oncological applications

Figure 5 High performance liquid chromatographic analysis of the non-purified iodine-123 labeled hypericin with Ultraviolet (254 nm) and radiometric detection. A: Ultraviolet-chromatogram of the starting reagent hypericin (Hyp) with a retention time of 19.18 min (upper part) and radiochromatogram (lower part) of ¹²³I-Hyp eluting at 22.13 min with a mean radiochemical yield of 95.4%; B: High performance liquid chromatographic analysis of the non-purified ¹²³I-Hyp at 48 h after labeling. A single narrow peak coming out at 21.90 min (lower part) suggests the in vitro stability of ¹²³I-Hyp over time. CPS: Count per second.