An overview of translational (radio)pharmaceutical research related to certain oncological and non-oncological applications

Figure 4 Macroscopic digital imaging of a mouse with acute ethanol-induced necrosis in the liver and muscle having received 5. 0 mg/kg hypericin in DMSO/PEG400/water (25:60:15, v/v/v). Under normal tungsten light, viable liver, intestines and muscle show normal appearances whereas hepatic infarction and muscle necrosis appear as white cheesy tissue (A₁, B₁, C₁). With a UV light of 254 nm, a bright red fluorescence from liver (A₂, B₂) and muscle necrosis (C₂) but a lack of fluorescent signal from the liver (A₂, B₂), viable muscle (C₂) and other abdominal structures were observed (A₂). DMSO: Dimethyl sulfoxide; PEG400: Polyethylene glycol 400; UV: Ultraviolet.