Hemogram-derived ratios as prognostic markers for major adverse cardiovascular events in patients with non-ST-segment elevation myocardial infarction

Table 4 Comparative analysis of hematological-derived indices among non-ST segment elevation myocardial infarction patients with major adverse cardiovascular event with lethal and non-lethal outcome, median (25^th-75^th percentiles)

HDR	Time	Lethal outcome (n = 35)	Non-lethal outcome (n = 51)	P value
NLR	T1	7.432 (4.542-12.551)	3.816 (2.423-5.783)	< 0.001
	T2	6.934 (3.672-12.165)	2.794 (2.167-5.580)	< 0.001
dNLR	T1	3.955 (2.721-6.764)	2.618 (1.667-3.675)	0.009
	T2	3.142 (2.056-5.686)	2.124 (1.436-3.295)	0.027
NPR	T1	0.032 (0.028-0.045)	0.030 (0.023-0.038)	0.090
	T2	0.031 (0.026-0.053)	0.026 (0.018-0.038)	0.047
NLPR	T1	0.029 (0.021-0.043)	0.016 (0.011-0.030)	0.005
	T2	0.035 (0.017-0.056)	0.013 (0.009-0.028)	< 0.001
PLR	T1	238.000 (150.420-303.448)	124.887 (92.446-191.566)	0.007
	T2	195.349 (149.359-353.846)	122.619 (83.529-169.186)	0.001
MNR	T1	0.067 (0.054-0.107)	0.111 (0.072-0.144)	0.028
	T2	0.074 (0.043-0.112)	0.131 (0.099-0.172)	0.000
MLR	T1	0.609 (0.424-0.892)	0.365 (0.272-0.509)	0.008
	T2	0.559 (0.428-0.756)	0.417 (0.282-0.553)	0.028
LMR	T1	1.641 (1.121-2.358)	2.742 (1.966-3.681)	0.008
	T2	1.788 (1.324-2.337)	2.400 (1.808-3.549)	0.028
LCR	T1	0.047 (0.015-0.163)	0.371 (0.084-0.748)	0.001
	T2	0.027 (0.008-0.102)	0.151 (0.027-0.424)	0.002
CRP/Ly	T1	21.145 (6.137-66.303)	2.321 (1.327-10.517)	0.001
	T2	37.403 (9.790-121.186)	6.630 (2.361-37.340)	0.002
SII	T1	1812.658 (950.655-3283.542)	919.518 (561.464-1277.483)	0.001
	T2	1778.563 (852.908-2800.333)	673.179 (413.184-1362.656)	0.001
AISI	T1	1399.338 (695.922-2265.644)	536.824 (370.566-910.278)	0.003
	T2	1353.896 (625.428-1836.498)	473.738 (293.227-1110.313)	0.011
SIRI	T1	4.511 (2.677-9.560)	2.473 (1.565-3.845)	0.003
	T2	4.653 (2.639-9.270)	2.244 (1.482-4.164)	0.009

HDR: Hematological-derived ratios; NLR: Neutrophil-to-lymphocyte ratio; dNLR: Derived neutrophil-to-lymphocyte ratio; NPR: Neutrophil-to-platelet ratio; NLPR: Neutrophil to lymphocyte and platelet ratio; PLR: Platelet-to-lymphocyte ratio; MNR: Monocyte to neutrophil ratio; MLR: Monocyte/lymphocyte ratio; LMR: Lymphocyte-to-monocyte ratio; LCR: Lymphocyte to C-reactive protein ratio; CRP/Ly: C-reactive protein-to-lymphocyte ratio; SII: Systemic immune inflammation index; AISI: Aggregate index of systemic inflammation; SIRI: Systemic inflammation response index; T1: Analysis at admission; T2: Analysis after 24 hours.