Fecal microbiota transplantation in allergic diseases

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 15, Issue 2

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

All Articles published online

Item

Count

PDF

HTML

493

Tables (1-2)

107

Sum=618

Publishing Process of This Article

Item

Count

Browse

Download

Sum=64

Jun 20, 2025 (publication date) through Jan 8, 2025

Times Cited of This Article

Journal Information of This Article

Publication Name

World Journal of Methodology

ISSN

2222-0682

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Minireviews

World J Methodol. Jun 20, 2025; 15(2): 101430
Published online Jun 20, 2025. doi: 10.5662/wjm.v15.i2.101430

Table 1 Potential roles of probiotics and fecal microbiota transplantation in alleviating or preventing allergic diseases[99]

Probiotics and FMT	Potential roles
Probiotics	Epithelial integrity ↑
	Tight junction protein expression ↑
	Bacterial translocation ↓
	Inflammatory cytokines such as IL-6, IL-8 and TNF-α ↓
	Restoration of Th1/Th2 balance
	Treg cell numbers and function, IL-10 and TGF-β ↑
	SCFAs production (especially butyrate) ↑
FMT	Pro-inflammatory cytokine secretion ↓
	Restoration of Th1/Th2 balance
	Stimulates T cell activity and leukocyte adhesion
	Change in intestinal bacterial diversity (Firmicutes, Bacteroidetes ↑/Proteobacteria, Actinobacteria ↓)
	Intestinal permeability ↓
	Epithelial integrity ↑
	SCFAs production ↑
	Intestinal pH ↓
	Bacterial adhesion to H₂O₂ ↑

SCFA: Short chain fatty acid; FMT: Fecal microbiota transplantation; TNF-α: Tumor necrosis factor-alpha; IFN-γ: Interferon-gamma; IL: Interleukin.

Citation: Tüsüz Önata E, Özdemir Ö. Fecal microbiota transplantation in allergic diseases. World J Methodol 2025; 15(2): 101430
URL: https://www.wjgnet.com/2222-0682/full/v15/i2/101430.htm
DOI: https://dx.doi.org/10.5662/wjm.v15.i2.101430