Early versus delayed necrosectomy in pancreatic necrosis: A population-based cohort study on readmission, healthcare utilization, and in-hospital mortality

Table 3 Clinical outcomes of all patients (index hospitalizations) who underwent pancreatic necrosectomy with a primary diagnosis of pancreatic necrosis, n (%)

Factor	Unmatched patients			Matched patients
	Within 48 hours (cases)	After 48 hours (controls)	P value	Within 48 hours (cases)	After 48 hours (controls)	P value
Total patients	420	889		349	375
Mechanical ventilation	14 (3.3)	155 (17.4)	< 0.001	< 10	41 (10.9)	< 0.001
Septic shock	38 (9.0)	239 (26.9)	< 0.001	28 (8.0)	73 (19.5)	< 0.001
Portal venous thrombosis	35 (8.3)	71 (8.0)	0.83	30 (8.6)	27 (7.2)	0.49
ICU-level admission	< 10	145 (16.3)	< 0.001	< 10	37 (9.9)	< 0.001
Acute kidney injury	64 (15.2)	330 (37.1)	< 0.001	54 (15.5)	114 (30.4)	< 0.001
New RRT during admission	15 (3.6)	43 (4.8)	0.30	13 (3.7)	< 10	0.20
Died during hospitalization	< 10	50 (5.6)	< 0.001	< 10	16 (4.3)	0.010

ICU: Intensive care unit; RRT: Renal replacement therapy. NOTE: According to the Healthcare Cost and Utilization Project Data Use Agreement, any individual table cell counts of ≤ 10 have been masked to ensure privacy and compliance. In such instances, data are designated as < 10.