Early versus delayed necrosectomy in pancreatic necrosis: A population-based cohort study on readmission, healthcare utilization, and in-hospital mortality

Table 2 Distribution of Elixhauser comorbidities among all patients (index hospitalizations) who underwent pancreatic necrosectomy with a primary diagnosis of pancreatic necrosis, n (%)

Factor	Unmatched patients			Matched patients
	Within 48 hours (cases)	After 48 hours (controls)	P value	Within 48 hours (cases)	After 48 hours (controls)	P value
Total patients	420	889		349	375
Congestive heart failure	35 (8.3)	81 (9.1)	0.64	30 (8.6)	29 (7.7)	0.67
Cardiac arrhythmias	55 (13.1)	287 (32.3)	< 0.001	48 (13.8)	58 (15.5)	0.51
Uncomplicated hypertension	230 (54.8)	458 (51.5)	0.27	194 (55.6)	200 (53.3)	0.54
Chronic pulmonary diseases	81 (19.3)	135 (15.2)	0.062	72 (20.6)	59 (15.7)	0.087
Uncomplicated diabetes	70 (16.7)	119 (13.4)	0.11	58 (16.6)	53 (14.1)	0.35
Complicated diabetes	66 (15.7)	170 (19.1)	0.13	55 (15.8)	64 (17.1)	0.64
Hypothyroidism	19 (4.5)	83 (9.3)	0.002	17 (4.9)	27 (7.2)	0.19
Renal failure	29 (6.9)	66 (7.4)	0.74	24 (6.9)	25 (6.7)	0.91
Liver disease	69 (16.4)	227 (25.5)	< 0.001	54 (15.5)	55 (14.7)	0.76
Coagulopathy	31 (7.4)	136 (15.3)	< 0.001	20 (5.7)	25 (6.7)	0.60
Obesity	60 (14.3)	204 (22.9)	< 0.001	43 (12.3)	43 (11.5)	0.72
Weight loss	118 (28.1)	444 (49.9)	< 0.001	108 (30.9)	124 (33.1)	0.54
Fluid and electrolyte disorder	227 (54.0)	634 (71.3)	<0.001	215 (61.6)	211 (56.3)	0.14
Iron-deficiency anemia	33 (7.9)	67 (7.5)	0.84	29 (8.3)	24 (6.4)	0.32
Alcohol abuse	110 (26.2)	271 (30.5)	0.11	97 (27.8)	108 (28.8)	0.76
Drug abuse	21 (5.0)	78 (8.8)	0.016	15 (4.3)	26 (6.9)	0.13
Depression	72 (17.1)	163 (18.3)	0.60	59 (16.9)	73 (19.5)	0.37
Complicated hypertension	32 (7.6)	86 (9.7)	0.23	26 (7.4)	27 (7.2)	0.90