Ensemble for evaluating diagnostic efficacy of non-invasive indices in predicting liver fibrosis in untreated hepatitis C virus population

doi:10.5662/wjm.v14.i3.91058

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World Journal of Methodology

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Methodol. Sep 20, 2024; 14(3): 91058
Published online Sep 20, 2024. doi: 10.5662/wjm.v14.i3.91058

Table 3 Correlation and significance with respect to liver stiffness measurement

Indices	R	P value
Routine investigations
Viral load	0.663	0.000^a
Hb	-0.169	0.092
INR	0.041	0.688
TSP	0.081	0.425
Albumin	-0.06	0.552
Bilirubin	0.149	0.14
AST	0.428	0.000^a
ALT	0.3	0.000^a
ALP	0.747	0.000^a
TLC	-0.391	0.000^a
Plt count	-0.473	0.000^a
Special investigations
Serum fibronectin	0.929	0.000^a
AAR	0.127	0.207
APRI	0.574	0.000^a
FIB-4	0.586	0.000^a

^aStatistically significant values with cut-off for significance set at < 0.05.

AAR: Alanine aminotransferase ratio; ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; APRI: Aspartate aminotransferase to platelet ratio index; AST: Aspartate aminotransferase; FIB-4: Fibrosis-4; Hb: Hemoglobin; INR: International normalized ratio; Plt: Platelet; TLC: Total leukocyte count; TSP: Total serum protein.

Citation: Kaur N, Goyal G, Garg R, Tapasvi C, Demirbaga U. Ensemble for evaluating diagnostic efficacy of non-invasive indices in predicting liver fibrosis in untreated hepatitis C virus population. World J Methodol 2024; 14(3): 91058
URL: https://www.wjgnet.com/2222-0682/full/v14/i3/91058.htm
DOI: https://dx.doi.org/10.5662/wjm.v14.i3.91058