Association of carbon monoxide poisonings and carboxyhemoglobin levels with COVID-19 and clinical severity

Table 3 Univariate and multivariate analysis of variables in patient groups

Patient groups	Univariate				Multivariate
	R square	β	t	P value	R square	β	t		P value
COHb (%)	0.452	0.672	19.837	< 0.001	0.589	0.166	2.287		0.023
Troponin (ng/mL)	0.485	0.696	21.197	< 0.001		0.258	3.457		0.001
Lactate (mmol/L)	0.468	0.684	20.501	< 0.001		0.241	2.462		0.014
PaCO2 (mmHg)	0.364	0.604	16.535	< 0.001		0.338	6.040		< 0.001
Bicarbonate (mmol/L)	0.309	-0.556	-14.659	< 0.001		0.259	2.306		0.022
Calcium (mmol/L)	0.028	-0.168	-3.723	< 0.001		0.072	2.141		0.033
Glucose (mg/dL)	0.243	0.494	12.420	< 0.001		0.166	3.532		< 0.001
Age (year)	0.187	0.433	10.483	< 0.001
pH	0.386	-0.621	-17.319	< 0.001
PaO2 (mmHg)	0.178	-0.422	-10.164	< 0.001
Potassium (mmol/L)	0.233	0.482	12.031	< 0.001
Sodium (mmol/L)	0.009	-0.095	-2.083	0.038
Base excess (mmol/L)	0.317	0.563	14.480	< 0.001

Bold values indicate significance at P < 0.05. COHb: Carboxyhemoglobin; PaCO₂: Partial pressure of carbon dioxide; pH: Potential of hydrogen; PaO₂: Partial arterial oxygen pressure.