Liver transplant allocation policies and outcomes in United States: A comprehensive review

Table 3 Organ procurement and transplantation network imaging classification for class 5 lesions in patients with cirrhosis

OPTN class	Description	Comments
0	Incomplete are technically in adequate study	No MELD exception points
5A	Lesion size ≥ 1 cm and ≤ 2 cm	Increased contrast enhancement in the late hepatic arterial phase along with either: (1) Wash out during late contrast phases and peripheral rim enhancement (capsule or pseudocapsule); and (2) Biopsy consistent with HCC
5A-g	Lesion size ≥ 1 cm and ≤ 2 cm	Increased contrast enhancement in the late hepatic arterial phase along with growth ≥ 50% documented on serial CT or MR obtained ≤ 6 mo apart
5B	Lesion size ≥ 2 cm and ≤ 5 cm	Increased contrast enhancement in the late hepatic arterial phase along with either: (1) Wash out during late contrast phases; (2) Peripheral rim enhancement (capsule or pseudocapsule); (3) Growth ≥ 50% documented on serial CT or MR obtained ≤ 6 mo apart in the absence of ablative therapy; and (4) Biopsy consistent with HCC
5T	Prior local regional therapy for HCC	Any residual lesion or perfusion defect at the site of prior class 5A, 5A-g, 5B lesion

OPTN: Organ procurement and transplantation network; MELD: Model for end-stage liver disease; HCC: Hepatocellular carcinoma.