Copyright
©The Author(s) 2021.
World J Methodol. May 20, 2021; 11(3): 23-45
Published online May 20, 2021. doi: 10.5662/wjm.v11.i3.23
Published online May 20, 2021. doi: 10.5662/wjm.v11.i3.23
Figure 3 The potential pathophysiological mechanisms linking obesity to cancer with special emphasis to the white adipose tissue remodelling.
WAT: White adipose tissue; IR: Insulin receptor; IGF-1R: Insulin-like growth factor-1 receptor; ER-α: Oestrogen receptor-α; Ob-R: Leptin-receptor; Adipo-R: Adiponectin-receptor; FFA: Free fatty acid; LD: Lipid droplets; ECM: Extracellular matrix; XIAP: X-linked inhibitor of apoptosis protein; VEGF: Vascular endothelial growth factor; HIF-1α: Hypoxia inducible factor-1α; GLUT4: Glucose transporter 4.
- Citation: Fernandez CJ, George AS, Subrahmanyan NA, Pappachan JM. Epidemiological link between obesity, type 2 diabetes mellitus and cancer. World J Methodol 2021; 11(3): 23-45
- URL: https://www.wjgnet.com/2222-0682/full/v11/i3/23.htm
- DOI: https://dx.doi.org/10.5662/wjm.v11.i3.23