Epidemiological burden of parents being the index cases of COVID-19 infected children

Table 4 Subgroup wise weighted prevalence of parent not being the index case in coronavirus disease 2019 infected children

Prevalence of COVID-19 infected children with parents not being the index case
Subgroup	Category	Number of studies	Number of COVID-19 positive children	Number of COVID-19 positive children with parent not being the index case	Weighted prevalence of COVID-19 positive children with parent not being the index case		95% prediction interval	Heterogeneity measures
					%	95% CI		I2 (%)	Q (P value)
Continent	Asia	8	28	8	25.0	0.03-0.55	0.0-0.9	31.8	0.17
	Europe	2	583	259	42.0	0.37-0.48	Inestimable	-	-
	North America	1	2	2	100.0	0.16-1.00	Inestimable	-	-
	South America	2	9	7	89.0	0.53-1.00	Inestimable	-	-
Country	21 European nations except France1	1	582	258	44.0	0.40-0.48	Inestimable	-	-
	France	1	1	1	100.0	0.03-1.00	Inestimable	-	-
	Brazil	1	2	0	0.0	0.00-0.84	Inestimable	-	-
	Chile	1	7	7	100.0	0.59-1.00	Inestimable	-	-
	China	3	11	2	13.0	0.00-0.46	Inestimable	-	-
	Iraq	1	3	0	0.0	0.00-0.71	Inestimable	-	-
	Singapore	1	9	2	22.0	0.03-0.60	Inestimable	-	-
	South Korea	2	4	3	82.0	0.23-1.00	Inestimable	-	-
	Taiwan	1	1	1	100.0	0.03-1.00	Inestimable	-	-
	United States	1	2	2	100.0	0.16-1.00	Inestimable	-	-
COVID-19 diagnosis in children	RT-PCR	12	620	276	50.0	0.24-0.76	0..0-1.0	63.4	0.00
	Rapid method	1	2	0	0.0	0.00-0.84	Inestimable	-	-
COVID-19 diagnosis in the index case	RT-PCR	10	36	15	40.0	0.06-0.80	0.0-1.0	68.9	0.00
	History	1	582	258	44.0	0.40-0.48	Inestimable	-	-
	Unclear	2	4	3	82.0	0.23-1.00	Inestimable	-	-
COVID-19 index patient clinical presentation	Symptomatic	8	20	6	27.0	0.00-0.67	0.0-1.0	44.3	0.08
	Unclear	5	602	270	64.0	0.28-0.94	0.0-1.0	77.2	0.00
Overall	NA	13	622	276	46.0	0.21-0.71	0.0-1.0	62.3	0.00

¹Austria, Belgium, Bulgaria, Croatia, Denmark, Estonia, Germany, Greece, Hungary, Ireland, Italy, Lithuania, Norway, Portugal, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey, and the United Kingdom. RT-PCR: Reverse transcription polymerase chain reaction; NA: Not applicable; COVID-19: Coronavirus disease 2019.