Prednisolone inhibits SaOS2 osteosarcoma cell proliferation by activating inducible nitric oxide synthase

Figure 4 Pharmacological inhibition of inducible nitric oxide synthase rescues SaOS2 cell growth. A: SaOS2 were treated with prednisolone in the presence or in the absence of L-NIL (100 μmol/L). Nitric oxide was measured as described (^bP < 0.01); B: Viable SaOS2 cells were counted after 4 d in the presence of different concentrations of prednisolone with or without L-NIL (^bP < 0.01). CTR: Control; L-NIL: l-N6-(iminoethyl)-lysine-HCl.