Pro- vs anti-stenotic capacities of type-I vs type-II human induced pluripotent-derived endothelial cells

Figure 4 Transplantation without immunosuppression. A-C: WI-operated femoral arteries transplanted with type-I or type-II iPSdECS were examined after 3 wk from PVVT in mice without αAGM1 administration. Photographs of HE-stained samples at high magnification, those at low magnification and calculated stenosis indexes (Av ± SD, n = 3) (C) were shown; D and E: HE staining (D) and calculated stenosis indexes (n = 3) (E) of WI-operated femoral arteries after 3 wk from ESdECs transplantation without αAGM1 administration. WI: Wire injury; iPSC: Induced pluripotent stem cell; VEC: Vascular endothelial cell; iPSdECs: iPSC-derived VECs; αAGM1: Anti-asialo GM1 monoclonal antibody; ESdECs: ESC-derived VECs.