Contributions of neutrophils to the adaptive immune response in autoimmune disease

doi:10.5528/wjtm.v4.i3.60

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World Journal of Translational Medicine

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transl Med. Dec 12, 2015; 4(3): 60-68
Published online Dec 12, 2015. doi: 10.5528/wjtm.v4.i3.60

Table 1 Surface markers used in identification of myeloid-derived suppressor cells

	Human	Mouse
MDSC	CD11b⁺ CD33⁺	CD11b⁺ Gr-1⁺
M-MDSC	CD11b⁺CD14⁺CD15^- HLA^-DR^-Lin^-	CD11b⁺ Ly6C⁺ Ly6G^-
G-MDSC	Cd11b⁺CD15⁺CD14^lo HLA^-DR^-Lin^-	CD11b⁺ Ly6G⁺ Ly6C⁺
Progenitor neutrophil	CD14^lo/neg CD15⁺ CD16^lo/neg
Mature neutrophil	CD14^lo/neg CD15⁺ CD16^hi CD33⁺ CD11b⁺ CD15⁺ CD66b⁺	CD11b⁺ Ly6G⁺

MDSC: Myeloid-derived suppressor cell; M-MDSC: Monocytic-MDSC; G-MDSC: Granulocytic-MDSC.

Citation: Pietrosimone KM, Liu P. Contributions of neutrophils to the adaptive immune response in autoimmune disease. World J Transl Med 2015; 4(3): 60-68
URL: https://www.wjgnet.com/2220-6132/full/v4/i3/60.htm
DOI: https://dx.doi.org/10.5528/wjtm.v4.i3.60