Epigenetics and DNA methylation in cancer

doi:10.5528/wjtm.v4.i1.11

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World Journal of Translational Medicine

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2220-6132

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transl Med. Apr 12, 2015; 4(1): 11-24
Published online Apr 12, 2015. doi: 10.5528/wjtm.v4.i1.11

Table 4 Comparison of methylation arrays vs ultra-deep sequencing for DNA methylation analysis

	Methylation arrays	Ultra-deep sequencing
CpG coverage	+	+++
Sensitivity	+++	++/+ (antibody-based)
Time consuming	++	++
Data analysis	+++	+
High-throughput	+++	+
Price	++	+/++ (price decreasing)

Adapted by Toraño et al[33], 2011.

Citation: Lattanzio L, Lo Nigro C. Epigenetics and DNA methylation in cancer. World J Transl Med 2015; 4(1): 11-24
URL: https://www.wjgnet.com/2220-6132/full/v4/i1/11.htm
DOI: https://dx.doi.org/10.5528/wjtm.v4.i1.11