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World J Transl Med. Dec 12, 2014; 3(3): 141-149
Published online Dec 12, 2014. doi: 10.5528/wjtm.v3.i3.141
Published online Dec 12, 2014. doi: 10.5528/wjtm.v3.i3.141
Figure 3 The ATP-sensitive K+ channels regulate insulin release in beta-cells.
Single nucleotide polymorphism in SUR1 and/or Kir6.2 genes may cause functional abnormalities of the ATP-sensitive K+ channel on the pancreatic β-cell membrane, leading to abnormalities in insulin secretion.
- Citation: Brunetti A, Brunetti FS, Chiefari E. Pharmacogenetics of type 2 diabetes mellitus: An example of success in clinical and translational medicine. World J Transl Med 2014; 3(3): 141-149
- URL: https://www.wjgnet.com/2220-6132/full/v3/i3/141.htm
- DOI: https://dx.doi.org/10.5528/wjtm.v3.i3.141