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World J Transl Med. Dec 12, 2013; 2(3): 32-35
Published online Dec 12, 2013. doi: 10.5528/wjtm.v2.i3.32
Published online Dec 12, 2013. doi: 10.5528/wjtm.v2.i3.32
Figure 3 Structure and activity of the most interesting dipeptidyl boroLeu developed by Milo et al[14].
IC-IC50/IC50 ratio → a measure of cell permeability, for which a value of 1.0 corresponds to 100%; CyT50/IC50 ratio → the relationship between cytotoxicity and inhibition, for which a value > 1.0 indicates that more than 50% inhibition is needed to kill 50% of the cells. CI: Cyclization index; IC: Intracellular; CyT50: Cytotoxicity.
- Citation: Micale N. Peptide-based boronates: How to achieve tissue specificity in anticancer therapy. World J Transl Med 2013; 2(3): 32-35
- URL: https://www.wjgnet.com/2220-6132/full/v2/i3/32.htm
- DOI: https://dx.doi.org/10.5528/wjtm.v2.i3.32