Cell-free mitochondrial DNA quantification in ischemic stroke patients for non-invasive and real-time monitoring of disease status

Figure 1 Difference in cell-free mitochondrial DNA concentrations and their diagnostic value in patients after treatment. A-C: Significantly increased levels of cell-free mitochondrial DNA (cf-mtDNA) were observed in patients at disease onset 24 h of treatment and 72 h of treatment compared to control individuals; D-F: Relative operative curve plots showing the diagnostic value of cf-mtDNA concentrations for discriminating the patients at disease onset 24 h of treatment, and 72 h of treatment. ^cP < 0.0001. AUC: Area under curve; cf-mtDNA: Cell-free mitochondrial DNA; ROC: Receiver operating characteristic.