Current progress and emerging technologies for generating extrapancreatic functional insulin-producing cells

doi:10.5528/wjtm.v10.i1.1

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Jun 26, 2022 (publication date) through Jul 24, 2024

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World Journal of Translational Medicine

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2220-6132

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transl Med. Jun 26, 2022; 10(1): 1-13
Published online Jun 26, 2022. doi: 10.5528/wjtm.v10.i1.1

Table 1 Summary of target cells and the degree of β-cell similarity

Characteristics	Target cell
Characteristics	Liver	Pituitary	Muscle	Kidney	Bone marrow
Endodermal origin	+	-	-	-	+
Possession of β-cell transcription factors	-	-	-	-	+
Glucose sensing system	+	-	-	+	-
Processing enzymes	-	+	-	+	-
Glucose-regulatable promoter	+	-	-	+	-
Exocytosis system	-	+	-	+	-
Autologous use	+	+	+	+	+
Allogenic use	-	-	-	-	+

Citation: Habeeb MA, Vishwakarma SK, Habeeb S, Khan AA. Current progress and emerging technologies for generating extrapancreatic functional insulin-producing cells. World J Transl Med 2022; 10(1): 1-13
URL: https://www.wjgnet.com/2220-6132/full/v10/i1/1.htm
DOI: https://dx.doi.org/10.5528/wjtm.v10.i1.1