Complement activation and long-term graft function in ABO-incompatible kidney transplantation

doi:10.5527/wjn.v8.i6.95

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Oct 27, 2019 (publication date) through Jan 31, 2025

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Nephrol. Oct 27, 2019; 8(6): 95-108
Published online Oct 27, 2019. doi: 10.5527/wjn.v8.i6.95

Table 2 Biopsy results

		ABO-incompatible (n = 27)	ABO-compatible (n = 108)	P value
Treated rejections, (%)		33	15	0.03
Acute antibody mediated rejection, (%)		4	1	0.36
Acute T-cell mediated rejection, (%)		30	14	0.05
	Grade IA, (%)	7	7
	Grade IB, (%)	4	3
	Grade IIA, (%)	15	3
	Grade IIB, (%)	4	1
	Grade III, (%)	0	0
Borderline acute T-cell mediated rejection		4	7	0.50
Donor specific antibodies (% positive)		0	6	0.17

P values calculated with chi-square test. Donor specific antibodies were measured according to local practice, i.e., at the discretion of the treating physician, and routinely at 8 wk after transplantation for Groningen patients and yearly for Amsterdam patients.

Citation: van Sandwijk MS, Klooster A, ten Berge IJ, Diepstra A, Florquin S, Hoelbeek JJ, Bemelman FJ, Sanders JS. Complement activation and long-term graft function in ABO-incompatible kidney transplantation. World J Nephrol 2019; 8(6): 95-108
URL: https://www.wjgnet.com/2220-6124/full/v8/i6/95.htm
DOI: https://dx.doi.org/10.5527/wjn.v8.i6.95