Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients

Table 3 Quality of life data presented as pool data and divided in two groups according to restless legs syndrome diagnosis

Variables	Patients pool data	RLS	Non-RLS	P value
SF-36 MCS	55.3 ± 16.7	46.6 ± 15.4	58.5 ± 16.1	0.004
95%CI	51.6 to 59.0	39.8 to 53.5	54.3 to 62.7
SF-36 PCS	51.8 ± 19.4	40.6 ± 18.1	56.1 ± 18.2	0.001
95%CI	47.5 to 56.1	32.5 to 48.6	51.2 to 60.8
SF-36 total score	55.1 ± 18.8	45.5 ± 17.7	58.7 ± 18.1	0.004
95%CI	51.0 to 59.3	37.6 to 53.3	54.0 to 63.4
Physical function	46.9 ± 29.1	38.4 ± 28.2	50.1 ± 29.1	0.107
95%CI	40.5 to 53.4	25.8 to 50.9	42.5 to 57.7
Role physical	45.3 ± 42.4	28.4 ± 38.8	51.6 ± 42.2	0.027
95%CI	35.9 to 54.7	11.2 to 45.6	40.6 to 42.7
Body pain	72.3 ± 23.1	63.9 ± 24.3	75.4 ± 22.0	0.045
95%CI	67.1 to 77.4	53.1 to 74.7	69.6 to 81.1
General health	47.0 ± 16.4	37.1 ± 14.5	50.7 ± 15.6	0.001
95%CI	43.4 to 50.6	30.6 to 43.5	46.6 to 54.8
Vitality	48.3 ± 16.1	36.1 ± 14.5	52.8 ± 14.2	0
95%CI	44.7 to 51.8	29.6 to 42.5	49.1 to 56.6
Social functioning	71.8 ± 20.8	65.5 ± 21.7	74.1 ± 20.2	0.098
95%CI	67.2 to 76.4	55.9 to 75.1	68.9 to 79.4
Mental health	52.2 ± 45.3	43.9 ± 47.5	55.3 ± 44.4	0.316
95%CI	42.2 to 62.3	22.8 to 65.0	43.7 to 66.9
Reported health	57.1 ± 12.1	50.7 ± 10.7	59.5 ± 11.8	0.003
95%CI	54.4 to 59.8	45.9 to 55.4	56.4 to 62.6

All data are mean ± SD (95%CI). SF-36: 36-Item Short Form Health Survey; MCS: Mental component score; PCS: Physical component score; RLS: Restless legs syndrome.