Copyright
©The Author(s) 2017.
World J Nephrol. Jul 6, 2017; 6(4): 176-187
Published online Jul 6, 2017. doi: 10.5527/wjn.v6.i4.176
Published online Jul 6, 2017. doi: 10.5527/wjn.v6.i4.176
Ref. | Population/setting | Study design | Overall study size | Albumin measurement | Hypoalbuminemia-related outcomes | |
AKI/ARF | Mortality | |||||
Tinti et al[45] | Liver transplantation | Prospective, observational | 24 | Preoperative albumin level | Lower albumin (3.1 g/dL vs 3.7 g/dL) predictive of ARF (P = 0.02) | ND |
Moore et al[48] | Renal transplantation | Retrospective, observational | 2763 | Albumin < 4.0 g/dL | Predictive of transplant failure: HR = 1.71 (95%CI: 1.18-2.49; P < 0.001) | ND |
Sang et al[46] | LDLT | Retrospective, observational, propensity score matching | 998 (incl. 249 matched pairs) | Albumin < 3.0 g/dL vs ≥ 3.0 g/dL before surgery | Albumin < 3.0 g/dL associated with increased AKI: OR = 0.42 (95%CI: 0.28-0.64; P < 0.001) | Survival rate lower with postoperative albumin < 3.0 g/dL (P = 0.02) |
Park et al[47] | LDLT | Retrospective, observational | 538 | Preoperative albumin level | Albumin < 3.5 g/dL: OR = 1.76 (95%CI: 1.05-2.94; P = 0.032) | ND |
Yang et al[49] | Renal transplantation | Retrospective, observational | 375 | Preoperative albumin < 3.5 g/dL vs 3.5-3.9 g/dL vs 4.0-4.4 g/dL vs ≥ 4.5 g/dL | Lowest risk of graft failure with ≥ 4.5 g/dL: HR = 0.536 (P = 0.029) vs < 3.5 g/dL | ND |
Chen et al[44] | Liver transplantation | Retrospective, observational, matching | 334 (incl. 118 matched pairs) | Preoperative albumin ≤ 3.5 g/dL | OR = 2.785 (95%CI: 1.427-5.434; P = 0.003); risk factor for posttransplantation AKI or ARF | ND |
- Citation: Wiedermann CJ, Wiedermann W, Joannidis M. Causal relationship between hypoalbuminemia and acute kidney injury. World J Nephrol 2017; 6(4): 176-187
- URL: https://www.wjgnet.com/2220-6124/full/v6/i4/176.htm
- DOI: https://dx.doi.org/10.5527/wjn.v6.i4.176