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Copyright ©The Author(s) 2017.
World J Nephrol. Jul 6, 2017; 6(4): 176-187
Published online Jul 6, 2017. doi: 10.5527/wjn.v6.i4.176
Table 4 Included studies on transplant surgery
Ref.Population/settingStudy designOverall study sizeAlbumin measurementHypoalbuminemia-related outcomes
AKI/ARFMortality
Tinti et al[45]Liver transplantationProspective, observational24Preoperative albumin levelLower albumin (3.1 g/dL vs 3.7 g/dL) predictive of ARF (P = 0.02)ND
Moore et al[48]Renal transplantationRetrospective, observational2763Albumin < 4.0 g/dLPredictive of transplant failure: HR = 1.71 (95%CI: 1.18-2.49; P < 0.001)ND
Sang et al[46]LDLTRetrospective, observational, propensity score matching998 (incl. 249 matched pairs)Albumin < 3.0 g/dL vs ≥ 3.0 g/dL before surgeryAlbumin < 3.0 g/dL associated with increased AKI: OR = 0.42 (95%CI: 0.28-0.64; P < 0.001)Survival rate lower with postoperative albumin < 3.0 g/dL (P = 0.02)
Park et al[47]LDLTRetrospective, observational538Preoperative albumin levelAlbumin < 3.5 g/dL: OR = 1.76 (95%CI: 1.05-2.94; P = 0.032)ND
Yang et al[49]Renal transplantationRetrospective, observational375Preoperative albumin < 3.5 g/dL vs 3.5-3.9 g/dL vs 4.0-4.4 g/dL vs ≥ 4.5 g/dLLowest risk of graft failure with ≥ 4.5 g/dL: HR = 0.536 (P = 0.029) vs < 3.5 g/dLND
Chen et al[44]Liver transplantationRetrospective, observational, matching334 (incl. 118 matched pairs)Preoperative albumin ≤ 3.5 g/dLOR = 2.785 (95%CI: 1.427-5.434; P = 0.003); risk factor for posttransplantation AKI or ARFND