Copyright
©The Author(s) 2017.
Figure 2 Potential roles of CLC-5 in endosomes.
A: In this model, Cl- accumulation by CLC-5 is critical for normal endocytosis; B: In contrast, 2Cl-/H+ exchange mode of CLC-5 activates V-ATPase which is required for maximal endosomal acidification.
- Citation: Satoh N, Suzuki M, Nakamura M, Suzuki A, Horita S, Seki G, Moriya K. Functional coupling of V-ATPase and CLC-5. World J Nephrol 2017; 6(1): 14-20
- URL: https://www.wjgnet.com/2220-6124/full/v6/i1/14.htm
- DOI: https://dx.doi.org/10.5527/wjn.v6.i1.14