Functional coupling of V-ATPase and CLC-5

doi:10.5527/wjn.v6.i1.14

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Jan 6, 2017 (publication date) through Oct 18, 2024

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Nephrol. Jan 6, 2017; 6(1): 14-20
Published online Jan 6, 2017. doi: 10.5527/wjn.v6.i1.14

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Figure 2 Potential roles of CLC-5 in endosomes. A: In this model, Cl^- accumulation by CLC-5 is critical for normal endocytosis; B: In contrast, 2Cl^-/H⁺ exchange mode of CLC-5 activates V-ATPase which is required for maximal endosomal acidification.

Citation: Satoh N, Suzuki M, Nakamura M, Suzuki A, Horita S, Seki G, Moriya K. Functional coupling of V-ATPase and CLC-5. World J Nephrol 2017; 6(1): 14-20
URL: https://www.wjgnet.com/2220-6124/full/v6/i1/14.htm
DOI: https://dx.doi.org/10.5527/wjn.v6.i1.14