Six end-stage renal disease patients benefited from first non-simultaneous single center 6-way kidney exchange transplantation in India

doi:10.5527/wjn.v5.i6.531

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Nov 6, 2016 (publication date) through Jul 6, 2024

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Nephrol. Nov 6, 2016; 5(6): 531-537
Published online Nov 6, 2016. doi: 10.5527/wjn.v5.i6.531

Table 2 Desensitisation protocol and outcome

	Patient 1	Patient 2	Patient 3
Before desensitization with original donor
LCM/DTT/AHG (%)	80/80/90	5/5/7	5/0/5
T/B FCM (MCS)	260/298	Neg/236	80/159
DSA class 1	A1 = 8000, B57 = 6200	No DSA	B44 = 4188, A31 1100
DSA class 2	DQ7 = 1600, DQ9 = 2200	DQ2 = 9000	No DSA
DP	8TPE + 8Bort/MP/IVIG + TAC/MMF	9TPE + 6Bort/MP/IVIG + R + TAC/MMF	4TPE + 4Bort/MP/IVIG + TAC/MMF
After desensitization with original donor
LCM	80/80/90	17/15/20	5/0/7
FCM	254/333	Neg/504	Neg/129
DSA class 1	A1 = 2000, B57 = 5500	No DSA	B44 = 4622, A31 = 1400
DSA class 2	DQ7 = 2000, DQ9 = 2000	DQ2 = 12000	No DSA
Side effects	Tuberculosis	Graft nephrectomy	Tuberculosis

TPE: Plasmapheresis; Bort: Bortezomib; MP: Methyl prednisolone; IVIG: Immunoglobulin; R: Rituximab; TAC: Tacrolimus; MMF: Mycophenolate mofetyl; DP: Desensitization protocol; LCM: Lymphocyte cross match; FCM: Flow cross match; DSA: Donor specific antibody; Neg: Negative; MCS: Median channel shift; DTT: Dithiothreitol; AHG: Antihuman globulin test.

Citation: Kute VB, Patel HV, Varyani UT, Shah PR, Modi PR, Shah VR, Rizvi SJ, Pal BC, Shah PS, Wakhare PS, Ghodela VA, Shinde SG, Trivedi VB, Patel MH, Trivedi HL. Six end-stage renal disease patients benefited from first non-simultaneous single center 6-way kidney exchange transplantation in India. World J Nephrol 2016; 5(6): 531-537
URL: https://www.wjgnet.com/2220-6124/full/v5/i6/531.htm
DOI: https://dx.doi.org/10.5527/wjn.v5.i6.531