Copyright
©The Author(s) 2016.
World J Nephrol. Nov 6, 2016; 5(6): 497-506
Published online Nov 6, 2016. doi: 10.5527/wjn.v5.i6.497
Published online Nov 6, 2016. doi: 10.5527/wjn.v5.i6.497
Table 1 Demographics and clinical characteristics of renal transplant recipients with/without BK polyomavirus nephropathy and comparison between those with BK polyomavirus nephropathy and BK viraemia n (%)
(-) BKVN (n = 217) | (+) BKVN (n = 9) | P value | (+) BKV (n = 19) | P value | |
Age (yr) | 48 (35.3-56.8) | 55 (34.9-60.5) | NS | 50 (27.1-60) | NS |
Gender (female) | 92 (42.3) | 3 (33.3) | NS | 6 (31.6) | NS |
Ethnicity | |||||
European | 131 (98.5) | 2 (1.5) | 0.038 | 11 (57.9) | 0.191 |
Asian | 32 (90.7) | 3 (9.3) | 4 (21.1) | ||
Māori and Pacific Islander | 54 (92.6) | 4 (7.4) | 4 (21.1) | ||
Cause of ESKF | |||||
Glomerulonephritis | 91 (41.9) | 5 (55.6) | NS | 8 (42.1) | NS |
Diabetes mellitus | 26 (12.0) | 2 (22.2) | 2 (10.5) | ||
Others | 55 (46.1) | 2 (22.2) | 9 (47.4) | ||
Co-morbidity | |||||
Diabetes mellitus | 26 (11.9) | 2 (22.2) | NS | 2 (10.5) | NS |
Hypertension | 130 (59.9) | 5 (55.5) | NS | 12 (63.2) | NS |
Cardiac disease | 31 (14.2) | 2 (22.2) | NS | 3 (15.8) | NS |
Dialysis vintage (yr) | 2 (0.2-5) | 5 (1-6) | NS | 2.5 (0-5) | NS |
Donor source (deceased) | 118 (54.3) | 9 (100) | 0.005 | 9 (47.4) | 0.01 |
HLA mismatch | 3 (2-4) | 4 (2.5-4) | NS | 3.5 (2-5) | NS |
Basiliximab induction | 95 (43.7) | 3 (33.3) | NS | 13 (68.4) | NS |
Tacrolimus | 92 (42.3) | 5 (55.6) | NS | 10 (52.6) | NS |
Cold ischaemia time (h) | 7 (4-15) | 19 (14.2-20.4) | 0.001 | 5.4 (4-12.5) | < 0.0001 |
AR at any time point | |||||
0 episode | 144 (66.4) | 3 (33.3) | 0.069 | 9 (47.4) | NS |
≥ 1 episode(s) | 73 (33.6%) | 6 (66.7) | 10 (52.6) | ||
AR before known BKV/BKVN status | |||||
10 → 0 episode | - | 3 (33.3) | 10 (52.6) | NS | |
11 →≥ 1 episode(s) | - | 6 (66.7) | 9 (47.6) | ||
Thymoglobulin for acute rejection | 33 (15.2) | 0 (0) | NS | 5 (26.3) | NS |
- Citation: Hsiao CY, Pilmore HL, Zhou L, de Zoysa JR. Outcomes of renal transplant recipients with BK virus infection and BK virus surveillance in the Auckland region from 2006 to 2012. World J Nephrol 2016; 5(6): 497-506
- URL: https://www.wjgnet.com/2220-6124/full/v5/i6/497.htm
- DOI: https://dx.doi.org/10.5527/wjn.v5.i6.497